Approved Uses for ARIMIDEX
ARIMIDEX is approved for adjuvant treatment (treatment following
surgery with or without radiation) of postmenopausal women with
hormone receptor-positive early breast cancer.
ARIMIDEX is approved for the initial treatment of postmenopausal
women with hormone receptor-positive or hormone receptor-unknown
locally advanced or metastatic breast cancer and for the treatment
of postmenopausal women with advanced breast cancer that has
progressed following treatment with tamoxifen. Patients with
hormone receptor-negative disease and patients who did not
previously respond to tamoxifen therapy rarely responded to
This medication is used to treat breast cancer in women who have
gone through "the change of life" (menopause). Anastrozole works by
lowering estrogen hormone levels to help shrink tumors and slow
How to use anastrozole
Take this medication by mouth with or without food, usually once a
day, or as directed by your doctor.
Use this medication regularly in order to get the most benefit from
it. Remember to use it at the same time each day.
Do not increase your dose or take this medication more often
without your doctor's approval. Your condition will not improve any
faster and the risk of serious side effects may be increased.
Since this drug can be absorbed through the skin, women who are
pregnant or who may become pregnant should not handle or break the
tablets of this medication.
Constipation, diarrhea, nausea, vomiting, upset stomach, loss of
appetite, body aches and pains, breast swelling/tenderness/pain,
headache, dry mouth, scratchy throat, increased cough, dizziness,
trouble sleeping, tiredness/weakness, flushing and sweating (hot
flashes/hot flushes), vaginal bleeding, hair thinning, and weight
change can occur. Changes in diet such as eating several small
meals may help lessen the chance of nausea and vomiting. If any of
these effects persist or worsen, notify your doctor or pharmacist
Remember that your doctor has prescribed this medication because he
or she has judged that the benefit to you is greater than the risk
of side effects. Many people using this medication do not have
serious side effects.
Tell your doctor right away if any of these unlikely but serious
side effects occur: mental/mood changes (e.g., depression),
excessive thirst, numbness/tingling/swelling of the hands or feet,
unusual tickling feeling, persistent cough, unusual vaginal
discharge/burning/itching/odor, unusually stiff muscles, muscle
pain, joint stiffness/pain, pain/redness/swelling of the arms or
legs, vision changes, bone pain, bone fracture, signs of infection
(e.g., fever, chills, persistent sore throat).
Seek immediate medical attention if any of these rare but very
serious side effects occur: chest pain, jaw/left arm pain, trouble
breathing, confusion, fainting, slurred speech, weakness on one
side of the body.
A very serious allergic reaction to this drug is unlikely, but seek
immediate medical attention if it occurs. Symptoms of a serious
allergic reaction may include: rash, itching/swelling (especially
of the face/tongue/throat), severe dizziness, trouble breathing.
This is not a complete list of possible side effects. If you notice
other effects not listed above, contact your doctor or pharmacist.
Before taking anastrozole, tell your doctor or pharmacist if you
are allergic to it; or if you have any other allergies. This
product may contain inactive ingredients, which can cause allergic
reactions or other problems. Talk to your pharmacist for more
Before using this medication, tell your doctor or pharmacist your
medical history, especially of: liver disease, high blood pressure,
heart disease (such as ischemic heart disease, history of chest
pain), brittle bone disease (osteoporosis), blood clots.
This drug may make you dizzy. Do not drive, use machinery, or do
any activity that requires alertness until you are sure you can
perform such activities safely. Limit alcoholic beverages.
Your healthcare professionals (e.g., doctor or pharmacist) may
already be aware of any possible drug interactions and may be
monitoring you for it. Do not start, stop, or change the dosage of
any medicine before checking with them first.
This drug should not be used with the following medications because
very serious interactions may occur: estrogens, tamoxifen.
If you are currently using any of these medications listed above,
tell your doctor or pharmacist before starting anastrozole.
Before using this medication, tell your doctor or pharmacist of all
prescription and nonprescription/herbal products you may use.
This document does not contain all possible interactions.
Therefore, before using this product, tell your doctor or
pharmacist of all the products you use. Keep a list of all your
medications with you, and share the list with your doctor and